Psychological Stress And Prolactin

Psychosocial stress increases prolactin in men and women
Trier Social Stress Test (TSST)

Stressful social interaction can elicit rapid increases in plasma prolactin in males

Case-control study: High prolactin associated with reporting more stressful life events
- Direction of causation not clear.

Rat study: Prolactin reduces anxiety
This suggests prolactin is produced in response to stress, in order to reduce anxiety.

In women prolactin surges associated with rage and humiliating experiences. Cortisol surges were related to surprise and shock but negatively associated with prolactin.